If you have five or more of the following symptoms that last for three weeks or longer, you may be suffering from major depression

• Feelings of unhappiness, hopelessness, pessimism
• Feelings of low self-esteem, worthlessness, guilt
• Loss of interest in hobbies, work, and other activities you usually enjoy, including sex
• Decreased energy, fatigue, feeling “slowed down”
• Insomnia, early morning awakening, or oversleeping
• Difficulty concentrating, remembering, making decisions
• Appetite changes—eating significantly less or more
• Irritability, restlessness, hostility
• Feeling anxious, stressed
• Recurring thoughts of death or suicide; suicide attempts
• Unexplained physical symptoms—such as headache, chronic indigestion, or pain—that do not respond to treatment