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Decitabine Injection (dee sye' ta been)
Other names: Dacogen
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Why is this medication prescribed?

Decitabine is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Decitabine is in a class of medications called hypomethylation agents. It works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.

How should this medication be used?

Decitabine comes as a powder to be to be added to fluid and injected slowly over 3 hours intravenously (into a vein) by a doctor or nurse in a medical office or hospital outpatient clinic. It is usually injected every 8 hours for 3 days. This treatment period is called a cycle, and the cycle may be repeated every 6 weeks for as long as your doctor recommends. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides that you will benefit from additional treatment.

Your doctor may also need to delay your treatment and reduce your dose if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with decitabine.

Your doctor will give you medication to prevent nausea and vomiting before you receive each dose of decitabine.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • Dacogen®
Last Revised January 02, 2008
American Society of Health-System Pharmacists
This information being provided is copyrighted by the American Society of Health-System Pharmacists, Inc., ASHP, Bethesda, Maryland.
©2010. All Rights Reserved.
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